Rapid HIV test approved by FDA

The US Food and Drug Administration (FDA) has approved a pioneering rapid HIV test that can simultaneously detect HIV-1 p24 antigen as well as antibodies to both HIV Type 1 and Type 2.

As well as providing faster diagnosis of HIV infection, the new test is also relatively simple to administer in remote ‘outreach’ settings. These two advantages have huge implications for combating AIDS in sub-Saharan Africa and other underdeveloped areas of the world.

The Alere Determine HIV-1/2 Ag/Ab Combo test is manufactured by Alere’s Israel-based Orgenics subsidiary. It can detect HIV antibodies and the HIV-1 p24 antigen in human serum, plasma, and venous or fingerstick whole-blood specimens.

Early tip-off

The HIV-1 p24 antigen test is not definitive but can act as an early ‘tip-off’ to the presence of HIV-1 infection.

When combined with the presence or absence of HIV-1 and HIV-2 antibodies, the combined test can differentiate an acute onset infection from a more established one.

In acute onset the blood specimen will test positive for HIV-1 p24 antigen but negative for the antibodies. In an established infection, the reverse is usually the case.

The test does not distinguish between antibodies to HIV-1 and HIV-2 so is not useful for screening of blood donors.

 

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Colloquium: “Covered California and HIV in LA County: Getting Everyone on the Same Page”

August 8, 2013 – Mr. Tom Donohoe, Director of the UCLA Pacific AIDS Education and Training Center, presented on the Affordable Care Act.  The presentation was given as part of the HIV Community and Research Colloquia Series hosted by the Los Angeles County (LAC) Commission on HIV and the UCLA Center for HIV Identification, Prevention, and Treatment Services (CHIPTS).   The presentation specifically focused on Covered California (California’s health insurance marketplace) and how it impacts consumers living with HIV in Los Angeles County.  Using case-based examples, the presentation helped to dispel misconceptions about what health care reform will do and not do for these populations infected and affected by HIV.   The event was attended by over 130 participants, including members of the LAC’s Commission on HIV, local HIV service providers, key community stakeholders, and consumers of HIV prevention and care services.   For a copy of the slides presented at the meeting, please click here.  To view the presentation, please click below.

The presentation was followed by a panel discussion.  The panelists included Derrick Butler, MD of THE Clinic, Aaron Fox of the LA Gay & Lesbian Center, John Riley of AIDS Project Los Angeles, Carlos Vega-Matos of Los Angeles County Division of HIV and STD Programs, and Michael Kelly.   To view the panel discussion, please click below.

 

CHIPTS hosts a monthly HIV Research and Community Colloquia Series in collaboration with the Los Angeles County Commission on HIV to highlight current issues and conversations surrounding HIV. Click here for past lectures and check out the events page for more information on future Colloquia presentations!

Billboards urging gay black men to get HIV-tested prompt controversy

Last year in South Los Angeles, billboards overlooking Crenshaw Boulevard showed two shirtless black men standing and embracing each other on a beach. “Our Love is Worth Protecting …. We Get Tested,” read the sign.

The ads, 10 in total, were developed by Jeffrey King, executive director of the Los Angeles advocacy group In the Meantime Men. The message’s purpose, King said, was to promote love and HIV testing among black men who have sex with men.

After the billboards went up, however, “the immediate reaction of the community was shock,” said the Rev. Eric P. Lee, president of the Greater Los Angeles chapter of the Southern Christian Leadership Conference. “It showed how we have commonly dealt with homosexuality in the community, which is ‘Don’t ask, don’t tell,’ a silence that doesn’t condemn or affirm.”

 

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U.S. Congress Moves Closer to Lifting Ban on Transplanting Organs From HIV-Positive Donors

A U.S. House of Representatives committee this week unanimously approved a bill approving transplants using organs taken from people infected with HIV. The HIV Organ Policy Equity Act would lift a nearly 3-decade-old federal ban on such transplants and allow expanded research into the outcomes of transplant patients. Similar legislation has already passed the Senate, and the bill’s advocates say that the policy shift could save hundreds of lives each year if it ultimately makes it into law.

“The shortage of organ donations in our country is a critical matter,” said Representative Lois Capps (D-CA), who introduced the bill, in a statement. “We need to begin to research the feasibility and safety of these transplants in hopes that more people can receive transplants, and more lives can be saved.”

Congress banned transplant of HIV-infected organs in 1988, when AIDS was rapidly spreading and little was known about how to prevent and treat it. A concerted effort to lift the ban began about 2 years ago, after a 2011 study published in the American Journal of Transplantation (AJT) concluded that the ban was outdated and that these organs could help fill a gap between supply and demand.

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Group Combats HIV/AIDS in Ethiopia with Community Conversations

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Persuading a people to let go of their traditions can be as difficult as bending steel but KMG-Ethiopia has been successful at doing just that. The organization began community conversations to stop dangerous cultural practices that often lead to HIV/AIDS and other sexual health issues.

According to KMG, traditions of female genital mutilation and forced marriage fuel HIV/AIDS in its country.

“Young women are given away to men who are much older than themselves. Young women in these communities do not have a choice,” KMG said. “This harmful practice violates young women’s rights to choice and freedom of association and puts them at risk of HIV and AIDS.”

The organization started their work by asking communities to elect peers who would be trained as facilitators. These facilitators now lead groups of 50 people in discussions that present basic facts about AIDS, relationship power structures and negotiating condom use.

Ethiopia has experienced a 90 percent drop in the transmission of HIV/AIDS between 2001 and 2011 – the largest decline in the rate of new infections of any country in Africa. And from 2005-2011, the country has seen a 53 percent drop in deaths caused by AIDS, from 113,825 to 53, 831 people.

New peer-led intervention helps individuals with HIV adhere to their treatment plans

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Individuals diagnosed with HIV nowadays can live long, healthy lives if they follow their medical treatment plans; however, nearly half of individuals with the virus fail to get needed medical help or to continue treatment, according to previous research. Now, a nursing researcher at the University of Missouri has developed a peer-led intervention that helps individuals with HIV adhere to their treatment plans that can improve their quality of life.

“Being ‘peered’ is different from being doctored, nursed or counseled,” said Maithe Enriquez, an associate professor in the MU Sinclair School of Nursing. “The peer educators in the intervention also have HIV, which gives them insider perspectives. Perhaps, the belief that only those living with HIV can truly understand what it’s like to live with the disease contributes to the meaningful connections between the educators and the patients struggling to adhere to treatment.”

Peer educators work with HIV patients to identify barriers that prevent them from taking medicines and going to appointments with their health care providers. Then, the peers help patients prioritize which barriers they can overcome most easily; subsequently, the peers and patients set goals and develop strategies to help the patients defeat their challenges.

Enriquez recently evaluated peer educators’ perceptions about their roles in patients’ treatment progress. Fifteen peer-educators gave accounts of their experiences working in HIV medical care settings. Enriquez analyzed the participants’ accounts and found that peers view their work as more than educating patients about treatment options; peers view themselves as role models, motivators, advocates and sources of social support. In addition, peers reported serving as liaisons between patients and their health care providers. Peers attributed their effectiveness with patients to their own longevity, which showed their mentees that they also could live long, healthy lives despite an HIV diagnosis. Enriquez said peer-led interventions have the potential to enhance HIV care and HIV-related health outcomes.

Getting to Wellness: A Roadmap for Improving the Health of Transgender Individuals in Los Angeles County

 

In response to HIV prevention priorities conveyed by the Los Angeles County Department of Public Health’s Division of HIV and STD Programs (DHSP), CHIPTS recently convened an independent time-limited consortium to identify best practices and potential models to address the health and wellness needs of transgender people in Los Angeles County.

Building upon foundational work previously conducted by others in the transgender and service provider communities, the CHIPTS Transgender Consortium developed a report that outlines the status of transgender health and wellness, particularly with respect to HIV disease; provides an overview of some of the services available to transgender people in Los Angeles County, and; describes opportunities to both strengthen and transform Los Angeles County’s response to the health and wellness needs of transgender people.

Please download the full report: Getting to Wellness: A Roadmap for Improving the Health of Transgender Individuals in Los Angeles County:  [Download not found]

Cedars-Sinai Medical Center Confirms Cutback to the Infectious Deseases Division

Fri, May 10 | By James F. Mills on http://www.wehoville.com

Hospital officials at Cedars-Sinai Medical Center in West Hollywood, Calif., have confirmed “some cutbacks” to the Infectious Diseases Division (IDD), which were originally announced internally in December 2012. These cuts will include HIV specialists Dr. Paula Gaut and Dr. David Hardy, who is also IDD’s director. Dr. Yoko Miyasak, an infectious disease researcher and HIV specialist, also will lose her hospital position unless she receives grant funding. Hardy warned that, while HIV/AIDS patients will continue to receive medical attention at the hospital, they will not have the expertise of “full-time, credentialed HIV specialists.” Patients also will not get the benefit of the hospital’s coordinated HIV care and research program.

Dr. Zab Mosenifar, executive vice chairman of Cedars-Sinai’s Department of Medicine, which includes the IDD, and Sally Stewart, the media relations manager, accused Hardy of spreading erroneous information. Their public statements disagree with Hardy’s on the number of positions that will be eliminated. Mosenifar emphasized that IDD is not closing. So far, no one has told patients where they should go for care, as HIV/AIDS patients usually see a doctor every three months. Hardy said he has been informing patients of the cutbacks as he wants them to be prepared, and he is encouraging them to get their medical records. According to Mosenifar, IDD’s fellowship training program will remain with Dr. Phillip Zakowski, a private practitioner and volunteer teacher who will assume Hardy’s responsibilities as part-time coordinator of the fellowship program.

One year ago, when the hospital closed its psychiatric division due to budget cuts, patients scrambled to find care and local mental health providers became overwhelmed. Jimmy Palmieri, West Hollywood human services commissioner, is worried that the situation will be repeated with HIV/AIDS providers. Palmieri is concerned about the patients and where they will find an immunologist for treatment. Since West Hollywood does not contract for services with Cedars-Sinai, the hospital was not required to notify the city of the cutbacks in its IDD. However, West Hollywood contracts with other organizations whose budgets may be affected if many of Cedars’ patients turn to them. Cedars-Sinai is required to offer a “community benefit program” under California law (SB 697) in exchange for nonprofit status. The hospital states on its Web site that one of the benefits it offers is “need.” In light of this statement, Hardy criticized the decision to reduce HIV/AIDS services, as West Hollywood is highly impacted by HIV/AIDS.

Program allows teens to text their sex questions

MONTREAL — To put it bluntly, talking to teenagers about sex is awkward.

But one Montreal group will try to engage the city’s youth in a serious discussion about sexuality — not in a classroom or through the use of a grainy VHS tape. AIDS Community Care Montreal is asking sexually curious teenagers to send them their questions about sex via text message.

“Sext ed” is the latest community-based initiative to try to fill the void left by Quebec’s ministry of education, which removed mandatory sex ed programs from public high schools in 2005. Project founders say they decided to upend traditional teaching models and reach out to youth directly on their cellphones.

“The obvious advantage of this is that it provides the person with anonymity and maybe makes it easier for them to ask a question without feeling judged or ashamed,” said Melissa Fuller, one of the project’s coordinators. “Often, youth have questions they don’t want to talk to an adult about. I mean, I’m now an adult and I don’t want to talk to adults (about sex). Also, people feel like they should know things already or they’ll be made fun of for the questions they ask.”

The project “soft launched” last month after contacting several high schools and community organizations. A wider launch is set for May 14 at ACCM’s headquarters on Plessis St. near Parc Lafontaine.

The questions people text to the service are reviewed by a volunteer, who researches the ACCM’s database and consults with sex ed professionals before sending a reply. Because the reply can only be 160 characters long, it includes a hyperlink to a more detailed response that allows users to access educational tools and resources on their own.

To ensure anonymity, the user’s cellphone number is scrambled and given a random number so that the person fielding questions can’t know where the message came from.

Fuller says the ACCM has been working on getting the Sext ed project off the ground for about a year. The lion’s share of the work has been assembling a guide of more than 1,000 frequently asked questions about sex that volunteers and users can consult at sexted.org.

“We went on a lot of Internet forums to see what people are asking and we used a lot of the questions people ask us when we do workshops,” said Fuller, also a sex columnist and former councillor at the Concordia Student Union. “For the questions we didn’t anticipate, we do more research and we add it to our database. It’s a constantly evolving process.”

Answers deal with subjects like where and when to get tested for sexually transmitted infections as well as safe sex practices. They can address pregnancy and other medical questions, but also the emotional side of sexuality, which Fuller says is too often overlooked by traditional sex ed courses.

“A big issue about not being educated about sex is that most people don’t know how to recognize unhealthy physical and emotional relationships,” Fuller said. “So we’re ready for questions about consent and we know that the questions may reveal themselves in subtle ways … It’s really important for us that the people texting us know there’s a caring person on the other end of that message. They need to feel supported.”

 

 

Experts say the need for comprehensive sex ed is backed up by a dramatic spike in certain types of STIs observed in Quebec and Canada over the last 10 years. For instance, a 2012 study conducted by Quebec’s Health Department found that the rate of chlamydia among young adults rose by 60 per cent between 2001 and 2011. Instances of syphilis and gonorrhea also saw a significant surge during this period.

Perhaps the most telling detail the study revealed is that the majority of teenagers in Quebec are having sex, and not all of them are using condoms. In the case of CEGEP students, the study found that about 67 per cent of respondents don’t always use a condom during sex with a “regular” partner, and about half said they don’t always use condoms with “occasional” partners.

Fuller says the ACCM has already been dealing with a handful of Montreal high schools and community groups and will expand its outreach program when it officially launches the service next week. Sext ed will also provide school teachers with tool kits on how to talk about sex with their students and what resources are available.

The organization has also been in touch with CEGEPs as well as Concordia and McGill University.

“The goal is to be in as many high schools as possible but also to be available for older students as well,” Fuller said. “People still have questions when they get to university. In fact, they may be even more shy to ask them because they feel ashamed for not knowing. We’ve been in touch with the resident advisers at Concordia University and they’re very receptive.”

Contacted by The Gazette on Tuesday, a spokesperson for Quebec’s Health Department said the government is working on implementing new, more comprehensive sex ed programs in the future. But the official could not say when details of the plan would be announced or give a rough estimate as to the amount of funds set aside to pay for it.

“I don’t think the government is malicious or anything; I think this is a conversation that’s difficult to have so that makes it easier to forget about,” Fuller said. “We wish there was better sex ed in high schools but we’re also happy to do what we can to help.”

To reach a Sext ed volunteer with a question, send a text message to 514-700-0445 or visit sexted.org

Read more: http://www.montrealgazette.com/health/Program+allows+teens+text+their+questions/8351263/story.html#ixzz2TIfnoi83