HIV Next Generation 2018 Information

► WHEN: January 19th, 2018, 9:00 AM-3:30 PM
► WHERE: UCLA Covel Commons

NEXT GEN 2018 is a free, one-day conference is to support the next generation of HIV researchers and service providers to work towards an end to AIDS through networking and sharing visions for future priorities. The conference will feature oral and poster presentations by students and emerging researchers from various institutions.

Below you will find the Agenda for the Conference as well as Parking Information and Directions:

2018 CHIPTS HIV Next Generation Conference - Agenda
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Feature Spotlight: Michael Li, PhD, MPH

Michael Li’s first introduction to public health was as a volunteer for a non-profit HIV services organization after completing his undergraduate education in molecular biology at the University of California, Irvine. His interest in the humanistic aspects of health grew from his involvement with vulnerable communities, eventually shifting his career to infectious disease case management and community health program management.  Throughout his studies, working towards a Master’s degree in Public Health at California State University, Fullerton and eventually his PhD in Preventive Medicine at the University of Southern California, Michael expanded upon his first-hand experiences to explore questions about how social and environmental factors impact health among sexual, gender-based, and racial minority communities.

After receiving his doctorate degree in 2017, Michael joined the Department of Family Medicine at UCLA as a postdoctoral scholar in addiction medicine under Dr. Steve Shoptaw.  His current research focus is in elucidating the effects of minority stress on stress biology and addiction, as well as their long-term implications for HIV infection and management of disease. He is investigating these research questions through an mSTUDY pilot and a large cohort study of patients in the Medical Care Coordination program in Los Angeles County. Michael has applied to the UCOP Fellowship and also plans to apply for an NIH K Award to advance his academic career in addiction medicine. In the near future, Michael hopes to work as an independent researcher in an academic setting where he can continue addressing the impact of society, human suffering, and biological systems on addiction.

Outside of work, Michael and his husband regularly attend dharma talks, practice meditation, and volunteer at their Jōdo Shinshū Buddhist temple in Orange County. On the side, they run a small woodworking business where they handcraft home décor and furnishings. They have two adorable dogs who love taking walks, receiving belly rubs, and eating peanut butter!

Each month, we’re featuring a member of our CHIPTS family and their work! To see past spotlights, check them out on the spotlights page and make sure to check back to see who we feature next!

Colloquium: “Sin Vergüenza Season 3- A Strategy to Reduce Stigma, Homophobia, Transphobia, and Addiction in LA”

January 4, 2018 – AltaMed’s English and Spanish telenovela webseries Sin Vergüenza (Without Shame) was developed to address a range of topics surrounding HIV in the Latino community overcoming stigma, seeking STD testing, treatment, behavioral health services, and violence. Earlier seasons encouraged viewers to seek HIV testing, promoted HIV medical care, treatment and the use of prevention methods including PrEP (Pre-Exposure Prophylaxis) and the impact of HIV on a family. The third season returns to address themes that are also heavily stigmatized but with an HIV lens including alcoholism, homophobia, and transphobia.

Natalie Sanchez and Hilda Sandoval from AltaMed discussed the process of developing an HIV social marketing campaign that is relevant and accessible to Latinos across multiple generations. They also addressed how the telenovela can be a channel to address the social determinants which are identified in the Los Angeles County HIV/AIDS Strategy 2020 and Beyond.  Ramon Garcia also spoke on the social impact of the series, breaking down the metrics and the reach of the videos and their goals with this new season. With the success of season’s one and two, Sanchez talked more about the use of entertaining content to increase awareness on HIV-related issues such as the ones they focused on in Season 3.

The colloquium finished up with a panel featuring the AltaMed team as well as Actor J.M. Longoria who plays Enrique Salazar and Actress Joanna Zoella who plays Christina Salazar who gave an in depth look at what it was like to play these characters and to meet people who were have watched the series.

You can download the flyer and presentation power point below and watch the full Colloquium presentation on YouTube!

No Stigma, No Shade, No Shame! Addressing Life, Love, Sex, and HIV Through Digital Media - Flyer
No Stigma, No Shade, No Shame: Addressing Life, Love, Sex and HIV Through Digital Media - Slides

CHIPTS hosts a monthly HIV Research and Community Colloquia Series in collaboration with the Los Angeles County Commission on HIV to highlight current issues and conversations surrounding HIV. Click here for past lectures and check out the events page for more information on future Colloquia presentations!

Most Influential Research of 2017 by Economists

Dr. Manisha Shah of CHIPTS’ Policy Impact Core at UCLA and Dr. Scott Cunningham of Baylor University recently published their paper entitled, “Decriminalizing Indoor Prostitution: Implications for Sexual Violence and Public Health,” in The Review of Economic Studies.   Based on their work, they were recognized as one of Quartz’s “13 economists on the research that shaped our world in 2017.”  Their work found that when Rhode Island legislature inadvertently decriminalized indoor prostitution in the state, it was linked to fewer reported STD cases and rape offenses.

Economist Jennifer Doleac of University of Virginia says, “This paper uses an unusual natural experiment in Rhode Island to measure the effect of decriminalizing indoor prostitution on public health, and the findings will surprise many… When indoor prostitution suddenly became legal, reported rape offenses fell by 30% and female gonorrhea incidence fell by over 40%. Perhaps it’s time to rethink our current policies in this area.”

Visit Quartz’s website to read the full list of 13 economists on the research that shaped our world in 2017.

Colloquium: “2017 Greater Los Angeles Homeless Count Results”

December 14, 2017 – Ms. JuHyun Sakota, Manager of Data and Research at the Los Angeles Homeless Services Authority (LAHSA), presented at this month’s Commission on HIV meeting, as part of the HIV Research and Community Colloquia Series.

She presented the results from the 2017 Greater Los Angeles Homeless Count.  The data gave an indepth perspective of the key characteristics of individuals experiencing homelessness in Los Angeles including demographic breakdowns by ethnicity, sex, age, sexual orientation, health conditions, and service planning areas in Los Angeles.  According to the data presented, 2 out of 100 person ages 18 and over experiencing homelessness in Los Angeles have HIV/AIDS based on self-reported data.  From their data, significant increases in persons who have HIV/AIDS were reported in service planning area 4 (Metro), 7 (East LA), and 8 (South Bay) from 2016 to 2017.

To learn more about the data presented, download the slides from the presentation below and check back soon as we’ll be uploading the lecture on Youtube:

Colloquium: LA Homeless Count and PLWH - Slides

 

CHIPTS hosts a monthly HIV Research and Community Colloquia Series in collaboration with the Los Angeles County Commission on HIV to highlight current issues and conversations surrounding HIV. Click here for past lectures and check out the events page for more information on future Colloquia presentations!

Evaluating Sex Behaviors and Substance Use in Pregnant Women in South Africa: Informing Interventions to Prevent HIV Acquisition and Transmission

Dr. Dvora Joseph Davey came to UCLA to present on her work in South Africa in a special guest lecture titled “Evaluating Sex Behaviors and Substance Use in Pregnant Women in South Africa: Informing Interventions to Prevent HIV Acquisition and Transmission.” With over 30 attendees in the audience ranging from well-versed researchers and faculty to postdoctoral students to undergraduate students, Dr. Joseph Davey gave a thorough overview of not only the current state of HIV risk and transmission in South Africa but also the studies that are currently in place, working to understand the institutions that affect these factors and aiming to find more effective ways to prevent transmission.

She highlighted three studies, the STIP – STI study in pregnancy in Tshwane and Cape Town, SexPP – a mixed methods study on the sex behavior of pregnant/postpartum women, and PrEP-PP – a study on PrEP in pregnant and postpartum women.

If you weren’t able to make Dr. Joseph Davey’s lecture, you can find her powerpoint slides below!

 

Evaluating Sex Behaviors and Substance Use in Pregnant Women in South Africa: Informing Interventions to Prevent HIV Acquisition and Transmission - Flyer

 

Evaluating Sex Behaviors and Substance Use in Pregnant Women in South Africa: Informing Interventions to Prevent HIV Acquisition and Transmission - Slides

 

World AIDS Day 2017 – A message from CHIPTS

On this annual day of remembrance, we pause to reflect on the state of science, policy, activism, treatment, and prevention and to renew energy and partnerships in our shared goal of ending HIV/AIDS.

We celebrate that improvements in HIV medications have made it so that people living with HIV can remain virally suppressed for long stretches of time – and that the life expectancy of those who are HIV-infected and on treatment is the same as those who are not HIV-infected. Treatment improves and maintains the health of those living with HIV and prevents transmission of HIV to others.

Treatment as Prevention (TasP) works!  Undetectable=Untransmittable (U=U).

We celebrate that we have powerful new tools to add to the existing HIV prevention armamentarium.   The use of an HIV medication can prevent transmission among people who are at high risk for HIV exposure, especially when the HIV medication is combined with behavioral prevention.

Pre-Exposure Prophylaxis (PrEP) works!

We celebrate that there is promise in the medication development pipeline! Not long from now, use of long-acting formulations of HIV medications will make it so that people living with HIV no longer need to take pills daily to maintain viral suppression. These long-acting HIV medications are likely to provide coverage for prevention, too—though that’s further in the future. New approaches, like using monoclonal antibodies, are under development and hold promise for treatment and prevention.

Never before has there been so many effective medications that can be combined with behavioral strategies for HIV treatment and prevention. Yet, this progress has not benefited all individuals who are living with or are at-risk for HIV/AIDS equally. Today, substantial numbers of people are living with HIV and are not virally suppressed. Too many people who are at risk for HIV cannot, will not, or do not take advantage of our powerful toolbox of HIV prevention methods.

For this reason, we propose a call, as a community, to renew policy and energy to address HIV treatment and prevention, in the U.S. and globally:

Let’s recognize a key truth that while most people can reach and sustain HIV treatment and prevention goals, there is a sizeable minority who cannot meet these goals with consistency.

Let’s recognize that there are real life reasons that interfere with people not being able to regularly meet their HIV treatment and prevention goals. These include chronic and disorganizing influences caused by co-occurring mental health and or substance use disorders, by stigma in all its forms, and by inconsistent access to food, housing, medical care, and other structural determinants of health.

Let’s recognize that scientific and programmatic efforts for those who cannot consistently achieve and sustain HIV treatment and prevention goals will be different (and more intensive) from that which works for the larger group who can. These efforts will likely need to include multiple disciplines and to be available when needed over the lifetime—not just one time.

Let’s use data better to figure out how best to allocate resources that meet the conditions faced both by the larger and by the smaller parts of our population who are living with or who are at risk for HIV.

Let’s build respect into the essence of this renewed direction. We do that by confronting head-on poverty, racism, sexism, homophobia, HIV stigma, homelessness at every level in our joint commitment to provide tangible packages of services that are accessible and acceptable to each and every one of us. This is foundational to a shared future with no more HIV infections.

We hope that on this World AIDS Day 2017 we can collectively harness our insights and energies to pursue these important new directions in science and programs that will get us to zero new HIV infections within the next decade.  Let us all feel renewed and recharged as we move forward together with commonality of purpose and mission.

Feature Spotlight: Emeka Okafor, PhD

Emeka Okafor, PhD is currently a postdoctoral fellow in the Division of Infectious Diseases, in the Departments of Medicine and Family Medicine at UCLA.  After receiving his Bachelor of Science degree in Biochemistry from the University of Lagos, Nigeria, he moved to Jacksonville to pursue his Master’s degree in Public Health at the University of North Florida. He then attended the University of Florida where he completed his doctoral program in epidemiology.  His research broadly focuses on biobehavioral epidemiology of drug use in persons living with or at-risk for HIV. In his research, Emeka was able to characterize long-term patterns and predictors of marijuana use and its impact on cognitive function and HIV-related clinical outcomes.

In September, 2016, Emeka moved to Los Angeles to begin his postdoctoral training at UCLA, focusing his research on understanding the biobehavioral pathways that link drug use to HIV-disease progression and behavioral treatment approaches for drug addiction. As part of his training, he plans to develop an expertise in developing, implementing, and evaluating behavioral treatments for drug addiction in vulnerable populations. Emeka’s long-term goal is to develop an independent research program at UCLA focused on drug addiction and HIV prevention among vulnerable groups. He’s currently working on a K01 proposal to study the mental health and clinical implications of medical marijuana use in persons living with HIV.

Emeka is also involved in other research activities linked to the UCLA Center for Behavioral and Addiction Medicine, including leading a sub-study under the HIV Prevention Trials Network (HPTN) 085 that aims to understand barriers to participating and retaining in HIV prevention clinical trials. Emeka’s involvement with HPTN recently deepened as he was selected for the HPTN Scholar program to study HIV status disclosure patterns and associations with HIV sexual risk behaviors among African American men who have sex with men.

Emeka is also quite active and enjoys playing soccer, ping-pong, and scrabble and loves heading to the outdoors for a hike with his wife when he’s not working. When he’s not listening to his favorite genres of hip-hop, reggae, and alternative R&B, he is likely watching his all-time favorite TV shows Prison Break, Breaking Bad, Narcos, or Game of Thrones!

Each month, we’re featuring a member of our CHIPTS family and their work! To see past spotlights, check them out on the spotlights page and make sure to check back to see who we feature next!

Scale-Up of Voluntary Medical Male Circumcision Services for HIV Prevention — 12 Countries in Southern and Eastern Africa, 2013–2016

Countries in Southern and Eastern Africa have the highest prevalence of human immunodeficiency virus (HIV) infection in the world; in 2015, 52% (approximately 19 million) of all persons living with HIV infection resided in these two regions.* Voluntary medical male circumcision (VMMC) reduces the risk for heterosexually acquired HIV infection among males by approximately 60% (1). As such, it is an essential component of the Joint United Nations Programme on HIV/AIDS (UNAIDS) strategy for ending acquired immunodeficiency syndrome (AIDS) by 2030 (2). Substantial progress toward achieving VMMC targets has been made in the 10 years since the World Health Organization (WHO) and UNAIDS recommended scale-up of VMMC for HIV prevention in 14 Southern and Eastern African countries with generalized HIV epidemics and low male circumcision prevalence (3). This has been enabled in part by nearly $2 billion in cumulative funding through the President’s Emergency Plan for AIDS Relief (PEPFAR), administered through multiple U.S. governmental agencies, including CDC, which has supported nearly half of all PEPFAR-supported VMMCs to date. Approximately 14.5 million VMMCs were performed globally during 2008–2016, which represented 70% of the original target of 20.8 million VMMCs in males aged 15–49 years through 2016 (4). Despite falling short of the target, these VMMCs are projected to avert 500,000 HIV infections by the end of 2030 (4). However, UNAIDS has estimated an additional 27 million VMMCs need to be performed by 2021 to meet the Fast Track targets (2). This report updates a previous report covering the period 2010–2012, when VMMC implementing partners supported by CDC performed approximately 1 million VMMCs in nine countries (5). During 2013–2016, these implementing partners performed nearly 5 million VMMCs in 12 countries. Meeting the global target will require redoubling current efforts and introducing novel strategies that increase demand among subgroups of males who have historically been reluctant to undergo VMMC…

(Full Article)

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Source: Figure 1, Figure 2

FDA Approves First Two-Drug Regimen for Certain Patients with HIV

November 21, 2017 – the U.S. Food and Drug Administration approved Juluca, the first complete treatment regimen containing only two drugs to treat certain adults with human immunodeficiency virus type 1 (HIV-1) instead of three or more drugs included in standard HIV treatment. Juluca is a fixed-dose tablet containing two previously approved drugs (dolutegravir and rilpivirine) to treat adults with HIV-1 infections whose virus is currently suppressed on a stable regimen for at least six months, with no history of treatment failure and no known substitutions associated with resistance to the individual components of Juluca.

“Limiting the number of drugs in any HIV treatment regimen can help reduce toxicity for patients,” said Debra Birnkrant, M.D., director of the Division of Antiviral Products in the FDA’s Center for Drug Evaluation and Research….

(Full Article)