Posts classified under: HIV -

MMT CARE for HIV Prevention: A Randomized Controlled Trial

Abstract: This project uses a combination prevention approach to respond to the urgent need for improved quality of services at methadone maintenance therapy clinics, provider-client interactions, and client outcomes.

We conduct the 5-year randomized controlled trial that targets methadone maintenance treatment (MMT) programs in China. Applying the principles of combination prevention, the intervention (MMT CARE) integrates psychosocial and behavioral components into a pharmacological framework for methadone maintenance. A total of 68 MMT clinics are randomly selected from five provinces. From each clinic, 6 service providers and 36 clients are recruited, totaling 408 providers and 2,448 clients in the study. The 68 clinics are randomized to 1) an MMT CARE intervention group or 2) a control group (34 clinics each). Service providers who complete the training conduct three individual motivational enhancement sessions with clients. Efficacy of the intervention is evaluated at baseline and at 6, 12, 18, and 24-month follow-ups.

Project Number: 4r01da033160-05

A Comprehensive Community-Based Strategy to Optimize the HIV Prevention and Treatment Continuum for Youth at HIV Risk, Acutely Infected and With Established HIV Infection

Abstract: America’s increasing HIV epidemic among youth aged 12-24 and our concurrent failure to identify, link to care, and achieve viral suppression among youth living with HIV (YLH) suggests the need to identify novel community-based strategies to leverage gateways and settings where high risk and infected youth can be engaged in HIV prevention and treatment. Scientific successes reducing HIV viral reservoirs among acutely infected infants, stopping HIV transmission from HIV-infected adults with undetectable viral loads, and documenting the efficacy of Treatment as Prevention (TASP) suggest strategies to reduce the trend of increasing adolescent HIV infections. This U19 will evaluate the usefulness of these advances for youth aged 12-24 at the highest risk of acquiring HIV- gay, bisexual, transgender youth (GBTY) and homeless youth (HY) – as well as youth living with HIV (YLH) in two HIV epicenters (Los Angeles and New Orleans). All GBTY and HY at five gay-identified community-based organizations (CBO) and homeless shelters will be screened over 18 months. From these screenings, a cohort of 220 YLH and 1,500 highest risk seronegative GBTY and HY will be formed. Over 24 months, this cohort will be repeatedly tested at four month intervals for sexually transmitted infections (STI) and serious drug use, and with 4th Gen HIV tests if seronegative, in order to identify acutely infected youth, engage youth in medical care, and monitor outcomes. Youth are triaged to: Study 1: Acute infection. Using 60 ARV-naive YLH with established infection as controls, we expect to identify 36 YLH with acute infection. All youth with acute infections will be aggressively treated with at least four highly potent antiretroviral therapies (ARV) and repeatedly assessed to examine if prolonged viral suppression is achieved, with reduced viral reservoirs to potentially allow ARV- free HIV remission. Study 2: Stepped care for YLH. Adapting strategies to manage chronic illnesses, we will conduct a RCT comparing a Standard Care Arm (repeated assessments every four month and an Automated Messaging and Monitoring Intervention [AMMI]) to Stepped Care. In the Stepped Care Arm, increasingly more intense interventions are delivered if viral load is detectable: a) the Standard Care Arm; b) an AMMI that is tailored to comorbidities of the specific YLH; or c) a Coach to support during crises, make treatment referrals, and brief interventions. Dried blood spots will monitor viral load and, on a small sample, ARV adherence over time. Study 3: Engaging seronegative youth in the HIV Prevention Continuum. Youth will be randomized to either: a) an AMMI Arm; b) Peer-Support plus AMMI Arm; c) eNavigator and an AMMI arm; or d) Peer-Support plus eNavigator plus AMMI Arm. Each condition aims to optimize the HIV Prevention Continuum. An interdisciplinary team of basic, clinical, and applied researchers with expertise in HIV, STI, behavioral interventions, biomedical interventions, CURE research, perinatal HIV, and a history of participating and coordinating multi-site RCT is participating on this U19 from six universities.

 

Project Number: 5U19HD089886-02

https://reporter.nih.gov/search/HbqgtLEtKUG1ysdAGWkuMQ/project-details/9353195

 

 

Contact PI/ Project Leader

ROTHERAM-BORUS, MARY JANE, PROFESSOR (ROTHERAM@UCLA.EDU)

 

 

Organization

UNIVERSITY OF CALIFORNIA LOS ANGELES

 

 

PUBLIC HEALTH RELEVANCE: Project Narrative HIV among youth has doubled in the last 15 years, with incidence expected to increase 39% by 2020. If acutely infected youth can be identified and treated during the period when their infectivity to others is 5-to 10-fold, we can reduce this expected rise as well as improve youth’s long-term health, reflected in smaller viral reservoirs. The set of studies in this U19 tests a comprehensive set of strategies for acutely infected youth, youth with established infection, and seronegative youth at highest risk of acquiring and transmitting HIV –with policy implications for communities and the Centers for Disease Control and Prevention.

 

 

FOA:  RFA-HD-16-035/ Study Section: ZHD1-DSR-N(50)1

 

Project Start Date:30-September-2016

Project End Date: 31-May-2021

Budget Start Date: 01-June-2017

Budget End Date: 31-May-2018

 

 

NIH Categorical Spending

Funding IC: EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT/ FY Total Cost by IC: $3,738,607

Multimodal Interventions to Improve Adherence to Oral Tenofovir/Emtricitabine as Pre-Exposure Prophylaxis in Women in Southern California

Abstract: Daily oral pre-exposure prophylaxis (PrEP) with tenofovir/emtricitabine (TDF/FTC) as part of a combination prevention package has been shown to be effective for HIV prevention in randomized control trials of MSM and heterosexual men and women at risk for HIV infection; however, some studies in African women have shown lack of efficacy that is believed to be in large part due to inadequate PrEP adherence. In addition, pharmacokinetic studies in women suggest that near-perfect adherence for TDF/FTC oral dosing may be more critical for protection against vaginal compared to rectal exposures. Taken together, these results imply that women may require substantially greater levels of adherence to oral TDF/FTC to effectively decrease HIV acquisition. Therefore, interventions to optimize adherence are particularly vital to maximizing the protective efficacy of PrEP for women. Although current FDA approval and CDC clinical guidelines for oral TDF/FTC as PrEP include at-risk women as candidates for use, limited clinical data exists on the use of PrEP in US women. Further research is needed to advance effective implementation, particularly taking into account the known challenges to achieving and maintaining high levels of adherence for women. In this demonstration project, we will evaluate adherence to, and acceptability of once-daily oral TDF/FTC as PrEP among HIV-uninfected women in Southern California who are at increased risk of HIV acquisition. Los Angeles and San Diego represent two of the top three counties in California of number of reported HIV/AIDS cases. In combination, they total over half of the number of HIV cases in the state supporting the need for ongoing prevention efforts in all at-risk populations (1). Working in tandem, the LAC PATH and CCTG partnership provides a unique opportunity to further collaborative research that has been fostered within the CHRP funding structure, capitalizing on the strengths of existing individual projects in MSM and transgender women.

SNS-Based Data Mining to Understand MSM Substance Use and HIV Risk Behavior

Abstract: HIV incidence among gay, bisexual and other men who have sex with men (hereafter MSM) continues to rise, driven in part by substance use. MSM are increasingly using social networking sites (SNS) to find substance use and sexual partners. However, no studies currently exist that use automated, real-time data collection and analysis procedures to monitor substance use and sexual partner seeking across the range of SNS platforms used by MSM to inform intervention development. This project will build on Routine Activities Theory to conduct research using SNS interactions to aid in understanding patterns of substance use and HIV risk behavior among MSM. During Phase 1, focus groups of MSM (n=~8/focus group; N=24) will be used to develop a lexicon for identifying substance use and sexual partner seeking among MSM via diverse SNS platforms. These findings will guide the development of a culturally congruent data collection and mining module (DCMM; internet software that systematically searches SNS to gather data in an analyzable format) with iterative feedback from a community advisory board (CAB) and pilot testing by MSM (n=6). During Phase 2, the DCMM will gather data from 50 MSM on SNS use (e.g., frequency, intensity) substance use and HIV risk/protective behaviors (e.g., content of profiles, postings). Risk behaviors will be assessed weekly via self- report and validated with biomarkers of risk behaviors to be collected at the end of the study period using a rapid oral HIV test and drug test via nail sample. This research will result in a subsequent R34 application to develop and test a just-in-time adaptive intervention (JTAI) using machine learning technology. The specific aims of the proposed research are to: (1) Develop and assess the utility of a culturally congruent DCMM to study the SNS use patterns, substance use and HIV risk and protective behaviors of MSM; (2) Determine associations between patterns of technology use, substance use and HIV risk behaviors among a sample of 50 MSM using a culturally congruent DCMM, self-report data collection and biomarkers for substance use and HIV; and (3) Evaluate the feasibility and the computational requirements of a just-in-time adaptive intervention to reduce substance use and HIV risk behavior among MSM. By devising and testing a culturally congruent DCMM to capture SNS data on MSM substance use and sexual partner seeking this study lays the building blocks to developing technology-based substance use and HIV prevention and treatment efforts tailored specifically for MSM.

 

Project Number: 5R03DA039752-02

https://reporter.nih.gov/search/UC7JBjMVIUuHREV5b0mu3A/project-details/9303328

 

 

Contact PI/ Project Leader

HOLLOWAY, IAN WALTER, ASSOCIATE PROFESSOR (holloway@luskin.ucla.edu)

 

 

Organization

UNIVERSITY OF CALIFORNIA LOS ANGELES

 

 

PUBLIC HEALTH RELEVANCE: Gay, bisexual and other men who have sex with men (hereafter MSM) use social networking sites (SNS) to locate substance use and sexual partners, which can increase their risk for HIV acquisition and transmission. This study will devise and test a culturally congruent data collection and mining module (DCMM) to capture large quantities of SNS data on MSM substance use and sexual partner seeking. This formative research has high public health significance as it can clarify the SNS partner seeking dynamics driving MSM’s substance use and sexual risk behaviors to inform culturally congruent technology-based substance use and HIV prevention and treatment efforts tailored specifically for MSM.

 

 

 

Project Start Date: 01-July-2016

Project End Date: 30-June-2020

Budget Start Date: 01-July-2017

Budget End Date: 30-June-2020

 

 

NIH Categorical Spending

Funding IC: NATIONAL INSTITUTE ON DRUG ABUSE / FY Total Cost by IC: $154,000

UCLA/Cambodia HIV/AIDS Training Program in Data Management and Analysis

Abstract: The prevalence of HIV/AIDS in Cambodia increased sharply in the 1990s, reaching upwards of 40% among high-risk populations.2 While the prevalence rate declined to approximately 0.9% by 2006, it remains inflated among high-risk groups.3 In the wake of the epidemic, the Cambodian government initiated national data collection and disease monitoring efforts that have produced rich, longitudinal data from HIV/AIDS treatment and surveillance programs. However, a shortage of professionals trained to manage and interpret these types of data, persists. The UCLA Department of Epidemiology and the Cambodian University of Health Sciences (UHS) propose a program to train a cohort of Cambodian public health professionals in the management, analysis and evaluation of secondary data. Trainees will have two tracks from which to choose. The UCLA MS/MPH track requires coursework in epidemiologic methods and principles, biostatistics, data management, behavioral sciences and HIV/AIDS epidemiology. This track also requires completion of a master’s project that must be relevant for HIV/AIDS policy development in Cambodia. The UCLA PhD track requires trainees complete core courses in epidemiology as well as courses in logic, causation and probability, the biology of HIV/AIDS, graduate statistics and pass a qualifying exam. Trainees then carry out a dissertation in Cambodia that is relevant to HIV/AIDS policy. The overall program will be assessed based on trainee progress and matriculation rates; thesis/dissertation quality, policy relevance and the proportion published; the program’s impact on UHS recruitment rates and trainee placement in national HIV/AIDS monitoring and data analysis roles.

 

Project Number: 5D43TW009590-04

https://reporter.nih.gov/search/2I1xWUcvb0-Q8T6WUaR75A/project-details/9267555

 

 

Contact PI/ Project Leader

GORBACH, PAMINA MAE , PROFESSOR (PGORBACH@UCLA.EDU)

 

 

Organization

UNIVERSITY OF CALIFORNIA LOS ANGELES

 

 

PUBLIC HEALTH RELEVANCE: The National Center for HIV/AIDS, Dermatology and STDs (NCHADS) in Cambodia has created databases of longitudinal HIV/AIDS, STI and behavioral data, opportunistic infections data, antiretroviral therapy and voluntary HIV counseling and testing behaviors. Cambodia seeks to integrate these databases to better facilitate longitudinal tracking and aggregate reporting, however a dearth of professionals skilled in data management, analysis and interpretation challenges this progress. The UCLA Department of Epidemiology and the Cambodian University of Health Sciences (UHS) propose to train a cohort of health professionals in the management and use of large, repeated-measures datasets to prepare and enable these professionals to better identify critical health trends, epidemiologic shifts and use their knowledge to inform HIV/AIDS policies and program improvements.

 

 

 

Project Start Date: 25-May-2014

Project End Date: 31-March-2019

Budget Start Date: 01-April-2017

Budget End Date: 31-March-2018

 

 

NIH Categorical Spending

Funding IC: NATIONAL INSTITUTE ON DRUG ABUSE + FOGARTY INTERNATIONAL CENTER / FY Total Cost by IC: $289,346

Natural History of AIDS in Homosexual Men

Abstract: The UCLA Center of the Multicenter AIDS Cohort Study proposes to continue to document clinical, immunologic, physiologic, behavioral, virologic, genetic and psychosocial changes in HIV-infected and -uninfected men-who-have-sex-with-men (MSM). This includes proposed studies to document these changes in MSM recruited 1983-4 and 2001-2, as well as plans to recruit new untreated and recently treated HIV-infected MSM (primarily African- and Hispanic- Americans), to maintain the cohort. The UCLA MACS will provide leadership and participation in the working groups, MACS-wide and local studies and research publications, and collaborative multi-cohort studies, as it has since the inception of the MACS 30 years ago. The UCLA MACS has recruited a large team of young and established co-investigators from a wide range of disciplines. These investigators have developed, and are continuing to develop, innovative proposals to advance our understanding of the pathophysiology, immunology, genetics and biobehavioral characteristics of treated and untreated HIV infection. The breadth, youth, experience and innovation of the UCLA MACS investigators, combined with the experience and commitment of the long-term staff, and our leadership of quality control procedures for immunologic and virologic measures and specimen processing, will continue to play an invaluable role in the success of the MACS over the next five years.

Project Number: 5U01SI035040-25

Adolescent Trials Network (ATN): Analytic Core

Abstract:  HIV interventions call for more advanced analytic approaches than traditional HIV studies have used. HIV prevention and treatment research trials have traditionally been conducted in a randomized controlled trial (RCT) framework where study participants, often recruited from social service agencies, are randomized into an intervention or standard of care condition and followed over time. Outcome measures consist of self-reported mental health and HIV transmission behaviors. Three large changes are necessary for adolescent studies in the modern era of HIV research. First, youth are often difficult to identify and engage in HIV care. Innovative recruitment strategies that make use of traditional and technology-based methods are necessary to maximize efforts. Second, NIH research priorities target biomedical HIV endpoints. Combination strategies that target HIV end points and comorbid conditions are needed. Lastly, researchers need to plan for intervention delivery in real-world settings. Youth deal with many complex issues, such as homelessness, that can impede access to and delivery of care, directly impacting biological outcome markers. Studies in the proposed U19 proposal will address current challenges in HIV research by using comprehensive youth engagement strategies and combination prevention strategies to address HIV end points and comorbidities. Statistical methods will be used to evaluate interventions in the RCT framework through complex multilevel models (MLM) to evaluate multiple end points over time. In addition, implementation science methods will be used to examine barriers to HIV care and engagement in clinic settings. The Analytic Core provides a range of technological, biomedical, and behavioral research expertise that will support research in the current U19 proposal. The Analytic Core is comprised of statisticians with expertise in fitting complex MLM in HIV studies that contain both biomarker and behavioral outcomes. Technologists are also a part of the Core and have used social media recruitment tools, mobile phone-based assessment, and cloud-based data storage in their own HIV research. The Analytic Core also fields expertise in implementation science and cost effectiveness analysis that will be used to address study aims. The Analytic Core will support research across U19 projects through the following specific aims. First, we will provide consultation on web- based tools that will enhance standard recruitment methods and finalize the recruitment sample of seronegative youth based on risk factors from a larger pool of seronegative youth. Second, data collection will be centralized to maximize data quality and security, minimize costs, and facilitate analysis. Dimagi CommCare software that we have used in prior HIV research will be used and provides an integrated package to provide HIPAA-compliant cloud-based data storage and mobile phone or web-based data entry. Third, Core scientists will conduct innovative analyses that include biological, engagement, and behavioral outcomes. Lastly, the Analytic Core will coordinate with the Management Core for timely dissemination of study findings.

 

Project Number: 5U19HD089886-02

https://reporter.nih.gov/search/lk6szwCxxUKY3-BsVeiAXQ/project-details/9353200

 

 

Contact PI/ Project Leader

COMULADA, WARREN SCOTT, PROFESSOR-IN-RESIDENCE (wcomulada@mednet.ucla.edu)

 

Organization

UNIVERSITY OF CALIFORNIA LOS ANGELES

 

 

FOA: RFA-HD-16-035 / Study Section: ZHD1-DSR-N

 

Project Start Date: N/A

Project End Date: N/A

Budget Start Date: 01-June-2017

Budget End Date: 31-May-2018

 

 

NIH Categorical Spending

Funding IC: EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT / FY Total Cost by IC:$502,513

STI Screening as a Combined HIV Prevention Platform for MSM in Peru

Abstract: Periodic counseling, testing, and treatment for rectal sexually transmitted infections (STIs) provides a multi- dimensional platform to integrate behavioral and biological HIV prevention strategies for men who have sex with men (MSM) in Peru. Rectal STIs like gonorrhea and chlamydia are key risk factors for HIV acquisition among MSM, both as indirect behavioral markers of recent unprotected receptive anal intercourse (URAI), and as inflammatory factors that increase cellular risk for HIV co-transmission. However, there have been no prospective studies of interventions addressing the specific behavioral and biological risk factors associated with rectal STI transmission or the potential impact on HIV transmission risk of integrating rectal GC/CT screening with other prevention services. We will use nucleic acid testing to screen 750 behaviorally high-risk MSM for rectal gonorrheal and/or chlamydial (GC/CT) infection. GC/CT-positive subjects will receive single-dose antibiotic treatment and either single-session Personal Cognitive Counseling (PCC) (n=50) or standard post-test counseling (n=50). A GC/CT-negative control group (n=50) will also be enrolled to compare biological outcomes including changes in levels of inflammatory cytokines following rectal STI. Aim 1: To adapt a Personalized Cognitive Counseling (PCC) model for use with MSM in Peru. Aim 2: To adapt and pre-test the SJEI and behavioral assessment instruments for use with MSM in Peru. Aim 3: To pilot a combined HIV prevention intervention based on rectal STI counseling, testing, and treatment for MSM in Peru. Estimates of feasibility/acceptability of the intervention, GC/CT prevalence/re-infection rate and the effect on behavioral and biological mediators of HIV infection will be used to plan an R01 evaluation of rectal STI surveillance as HIV prevention for MSM in Peru.

Project Number: 5R01MH105272-03

Transprep: Social Network-Based PreP Adherence for Transgender Women in Peru

Abstract: The effectiveness of Pre-Exposure Prophylaxis (PrEP) for reducing HIV transmission is strongly dependent on adherence, which is influenced by individual, social, and structural factors. We propose a social network-based intervention to promote PrEP adherence among transgender women (TW) in Lima, Peru: 1) Formative research. To optimize content for a PrEP adherence intervention, we will conduct semi- structured interviews and focus groups. Results will be used to refine the PrEP adherence intervention. 2) To conduct an open evaluation of a social network-based PrEP adherence intervention for TW in Peru. The intervention model will be piloted with a small group of 5-10 TW. Data will be used to finalize the study design and assessment tools for a pilot randomized controlled trial (RCT). 3) To conduct a pilot RCT of a social network-based PrEP adherence intervention for TW in Peru. We plan to randomize 8 social network-based clusters of TW that to either a network-based PrEP adherence intervention or standardized PrEP adherence counseling. The primary outcome will be PrEP adherence. The intervention will use a combination of individual counseling, group workshops, social media-based network interactions, and practical support tools to promote PrEP adherence among TW. Individual Counseling: Participants will complete two biweekly counseling sessions addressing PrEP use and HIV prevention. The goals of individual counseling are to introduce PrEP as an HIV prevention tool and address basic issues of PrEP adherence as part of a comprehensive HIV prevention strategy. Group Workshops. Group workshops will establish a common understanding of PrEP as a central component of comprehensive HIV prevention, address the importance of PrEP adherence, develop practical strategies to support adherence, and generate and maintain norms of HIV prevention and PrEP adherence within the peer group. Biweekly maintenance meetings will address ongoing issues related to PrEP use and adherence. Social Network Interactions. The social network component of the intervention will include structured social media platforms to educate, motivate, and promote discussions of PrEP adherence within the participant network, unstructured participant-generated interactions to articulate and reinforce newly developed social norms within the network, and practical tools to support daily adherence. PrEP Use. Participants will be provided with daily Truvada for the 6-month study period. Assessment Procedures, Timing and Measures. There will be three major assessment points: baseline, short-term outcome (3 month), and long-term outcome (6 month). The primary outcome of the intervention will be a comparison of PrEP adherence in the intervention and control groups. Findings will be used to support an NIH-funded R01 proposal using social networks of TW and social media technologies to generate, implement, and reinforce new social norms of PrEP adherence, sexual risk behavior, and HIV prevention.

 

Project Number: 5R34MH104072-03

https://reporter.nih.gov/search/clOmBeNL3EiQvAvH8MjhLQ/project-details/9119194

 

 

Contact PI/ Project Leader

CLARK, JESSE LAWTON, ASSISTANT PROFESSOR-IN-RESIDENCE (jlclark@mednet.ucla.edu)

 

 

Organization

UNIVERSITY OF CALIFORNIA LOS ANGELES

 

 

PUBLIC HEALTH RELEVANCE: Pre-exposure prophylaxis (PrEP) is an important new tool for HIV prevention, but is highly dependent on patient adherence. Our study the uses social networks of transgender women in Peru as a framework to promote PrEP adherence in socially marginalized communities at high risk for HIV infection.

 

FOA: PAR-11-278/ Study Section:ZMH1-ERB-M(02)

 

Project Start Date: 01-August-2014

Project End Date: 31-July-2018

Budget Start Date: 01-August-2016

Budget End Date: 31-July-2018

 

 

NIH Categorical Spending

Funding IC: NATIONAL INSTITUTE OF MENTAL HEALTH / FY Total Cost by IC: $141,615

South American Program in HIV Prevention Research (SAPHIR)

Abstract: Effective HIV prevention interventions require the integrated analysis of behavioral, biological, and social transmission patterns within specific cultural contexts. The South American Program in HIV Prevention Research (SAPHIR) program offers developing investigators from the U.S. an intensive, structured program of education and practical research training on comprehensive HIV prevention in an international environment. Specific Aim 1. To provide researchers from the U.S. with a structured program of education and training based on a focused research topic within the field of HIV prevention in Latin America. SAPHIR program trainees are paired with research mentors from the U.S. and Latin America to develop an independent research program incorporating both secondary analysis of existing data and design of an original research study protocol. Potential research topics include behavioral, epidemiological, clinical and laboratory issues related to HIV prevention within specific Latin American contexts. Specific Aim 2. To provide a program of didactic instruction and interactive seminars addressing integrated approaches to HIV prevention in international settings. The training program includes a weekly series of lectures and seminars on key areas of global HIV prevention, including lectures, journal clubs, research presentations, and ethics case conferences. The conceptual framework for the educational program is based on the intersection of scientific disciplines through the lens of comprehensive HIV prevention. Specific Aim 3. To build the capacity of a collaborative network of international investigators and research centers with individual areas of scientific expertise to produce integrated approaches to HIV prevention research in Latin America. In addition to practical training for young investigators, a secondary aim of the program is to promote inter-institutional collaboration and capacity-building for participating research centers. Graduates of the program accomplish the following goals: 1) Acquire a foundation of knowledge in the four core areas of comprehensive HIV prevention (epidemiology, diagnosis, treatment, and prevention); 2) Complete a secondary data analysis and prepare a corresponding abstract for submission to an international scientific conference; 3) Design an independent research sub-study; 4) Prepare a study protocol that meets requirements for the ethical conduct of research with human subjects as defined by the UCLA Office for Human Research Participant Protection; 5) Submit a funding proposal for peer review and receive a written summary statement; and 6) Present results of their research in a local community venue and at an annual conference of program trainees and mentors. All SAPHIR graduates acquire the exposure, skills, and practical experience necessary to gain admission to competitive post-doctoral training programs and to build an academic career in international HIV prevention research.

Learn more about the SAPHIR Project under our Education tab.

 

Project Number: 5R25MH087222-07

https://reporter.nih.gov/search/m0rL1dvIQU6YTEJnprA9eg/project-details/9297356

 

 

Contact PI/ Project Leader

CLARK, JESSE LAWTON, ASSISTANT PROFESSOR-IN-RESIDENCE (jlclark@mednet.ucla.edu)

 

 

Organization

UNIVERSITY OF CALIFORNIA LOS ANGELES

 

 

PUBLIC HEALTH RELEVANCE: Relevance to Public Health The newest generation of physician scholars recognizes the need for global approaches to HIV prevention but lacks structured opportunities for research training in international sites. Our dedicated program of education and practical training in international HIV prevention studies fills an important deficit in current AIDS research.

 

FOA: PAR-15-145/ Study Section: ZMH1-ERB-I(03)

 

Project Start Date:01-August-2011

Project End Date: 31-May-2021

Budget Start Date:01-June-2017

Budget End Date: 31-May-2018

 

 

NIH Categorical Spending

Funding IC: NATIONAL INSTITUTE OF MENTAL HEALTH / FY Total Cost by IC:$269,645

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