Dear colleagues,

The UCLA Clinical and Translational Science Institute (CTSI) in collaboration with UCLA CHIPTS and UCLA-CDU CFAR are hosting the Fall 2024 CTSI Translational Science Seminar on Tuesday, October 15, 2024, from 12:00 PM-1:00 PM.

This upcoming seminar entitled, “Translation in Practice: Advancing HIV Treatment and Prevention for Everyone” will highlight the translational science journey of long-acting injectables for HIV treatment and prevention. The tools to bring a halt to new HIV transmissions have long been available, however, many people at risk for or with HIV struggle to remain on these medications. Long-acting injectables present new strategies for addressing these issues.

CHIPTS’ own Drs. Raphael Landovitz, Dilara Üsküp, and Ron Brooks are among the featured speakers who will discuss different phases of the journey of this innovation from the lab to addressing current implementation challenges in communities.

This event is in-person at the MacDonald Research Laboratories (MRL) Room 1-441.

Register here! Registered participants will receive lunch during the seminar.

For questions, please contact CTSIWD@mednet.ucla.edu.

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The California Statewide HIV and Aging Educational Initiative in partnership with Santa Clara County Getting to Zero invites you to participate in a Statewide Skill-Building Symposium: Addressing Mental Health among Older Adults with HIV on Wednesday, June 5, 2024, from 8:30 AM-4:30 PM PT, at Campbell Community Center’s Orchard City Banquet Hall.

Mental health is a critical concern among older adults with HIV in California. In honor of HIV Long-Term Survivors Awareness Day, this one-day, in-person symposium will help equip California service providers and frontline staff to better address the mental health needs of older adults with HIV, including the unique needs of long-term survivors. Leading experts will offer engaging, interactive presentations on the intersection of mental health and loneliness & isolation, physical & cognitive decline, substance use, and more! By the end of the symposium, participants will be able to:

1. Identify at least three key issues impacting mental health among older adults with HIV in California.
2. Describe at least two strategies to address key issues impacting mental health among older adults with HIV in California.
3. Apply at least one strategy to help meet the mental health needs of older adults with HIV in their own work.

Registration is free and required for attendance and includes a continental breakfast and lunch. Capacity is limited and registration will close once capacity has been reached, so please register early to ensure you have an opportunity to participate! A hotel room block with discounted rates is available to symposium participants near the venue at Larkspur Landing, Campbell. Continuing education credit for the symposium is being provided by the Pacific AIDS Education & Training Center – Bay Area, North, and Central Coast (BANCC).

Learn more and register here: https://paetc.caspio.com/dp/050e700090280c9da9194a3daf9c?ER_ID=20017702

The California Statewide HIV and Aging Educational Initiative is a collaborative capacity-building initiative led by the UCLA Center for HIV Identification, Prevention and Treatment Services (CHIPTS), APLA Health, the Pacific AIDS Education and Training Center (PAETC)—LA and BANCC, and the San Francisco AIDS Foundation. If you have any questions, please contact Elena Rosenberg-Carlson at erosenberg-carlson@mednet.ucla.edu.

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Please join our UCLA Rapid, Rigorous, Relevant (3R) Implementation Science Hub for the next Implementation Science Beachside Chat titled Qualitative Research in Implementation Science: Reflections on the Last Five Years coming up on Friday, February 9, from 9-10 AM PT! Hosted by Dr. Alison Hamilton, this Chat will feature an engaging discussion with the esteemed members of the Qualitative Research in Implementation Science (QualRIS) group commissioned by the National Cancer Institute to develop a White Paper on Qualitative Research in Implementation Science in 2019.

Please REGISTER HERE to join, and share this opportunity with your networks! A flyer is below.

To access past Chats and methods workshops hosted by the Hub, check out our YouTube playlist. If you have any questions, please contact Elena Rosenberg-Carlson at ERosenberg-Carlson@mednet.ucla.edu.

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Center for HIV Identification, Prevention, and Treatment Services (CHIPTS) Methods Seminar

Health Policy Modeling Using Simulations: Cost-Effectiveness Analysis of Pre-exposure Prophylaxis (PrEP) for the Prevention of HIV Among Men Who Have Sex with Men (MSM) in Los Angeles County

Sze-chuan Suen, PhD
Assistant Professor
Epstein Department of Industrial and Systems Engineering
University of Southern California

Tuesday, November 13, 2pm – 3pm
Center for Community Health, UCLA Wilshire Center
10920 Wilshire Blvd, Suite 350, Room 350-46 (Conference Room)

*** LIGHT REFRESHMENTS WILL BE SERVED ***
We will begin promptly at 2:00 p.m.

Health policy modeling and cost-effectiveness analysis can be useful tools to inform policymakers who must decide how to allocate scarce resources between interventions.  Accurate modeling of the disease dynamics must reflect population trends, disease transmission rates, treatment uptake and adherence, and mortality risks before and after the intervention. Dynamic transmission models can capture these patterns, but they must be carefully calibrated and validated to empirical data.

Here, we use a dynamic simulation model of HIV in Los Angeles County to evaluate the cost-effectiveness of Pre-exposure Prophylaxis (PrEP) compared to interventions to improve testing and treatment for HIV among men who have sex with men (MSM).  We will discuss the model structure, inputs, and output capabilities of the published model, and we will also discuss limitations and concerns with these types of models.

This event is hosted by the Center for HIV Identification, Prevention, and Treatment Services (CHIPTS) and made possible by funds from the National Institute of Mental Health (MH058107).

Sean Young, PhD
Associate Professor
UCLA Department of Family Medicine
Executive Director of the University of California Institute for Prediction Technology (UCIPT)

Tuesday, December 11, 2pm – 3pm

Center for Community Health, UCLA Wilshire Center
10920 Wilshire Blvd., Suite 350, Room 350-46 (Conference Room)

*** LIGHT REFRESHMENTS WILL BE SERVED ***
We will begin promptly at 2:00 p.m.

Social data from technologies such as social media, online search, and mobile apps are being used to better understand and predict real-world events and outcomes, including HIV transmission. For example, researchers in the health and medical space have been studying whether social data might be used to monitor and predict outbreaks of disease, susceptibility to disease, and patient response to treatment. This talk with provide an overview of the field of work on prediction technology using social data, such as 1) how Twitter is being used to predict HIV risk behaviors and syphilis transmission, 2) how google search terms are being used to predict political events, and 3) the ethical issues behind this approach (e.g., social media users’ perceptions of having their data used for research).

Panteha Hayati Rezvan, PhD
Postdoctoral Fellow
UCLA Global Center for Children and Families
CHIPTS

Tuesday, October 9, 2pm – 3pm

Center for Community Health, UCLA Wilshire Center
10920 Wilshire Blvd., Suite 350, Room 350-46 (Conference Room)

*** LIGHT REFRESHMENTS WILL BE SERVED ***
We will begin promptly at 2:00 p.m.

Missing data are frequently encountered in longitudinal studies with repeated follow-up waves and have the potential to induce bias and reduce precision if not handled properly. Multiple imputation (MI) has emerged as a successful framework for addressing missing data problems, but in longitudinal settings, incorporating all variables that predict other data values or that predict non-response can lead to large imputation models. Consequent convergence issues due to high correlations between variables carry the potential for over specified models, and accompanying bias and variance inflation.

The first part of this seminar will provide an overview of multiple imputation strategies with a focus on contextual factors that contribute to sensitivity in research findings. The second part of the seminar will focus on the application of multilevel multiple imputation using data collected through a HIV prevention community-clustered randomized controlled trial in South Africa. To assess the robustness of inferences to proper handling of missing data in outcomes and exposure, I will illustrate two MI strategies developed within the joint-modeling and the fully-conditional specification frameworks, and will compare the findings with the results obtained from longitudinal mixed-effects models. Findings from this study will be discussed with the aim of offering methodological insights with potential application to behavioral and biomedical research settings.

This event is hosted by the Center for HIV Identification, Prevention, and Treatment Services (CHIPTS) and made possible by funds from the National Institute of Mental Health (MH058107).

 

Center for HIV Identification, Prevention, and Treatment Services (CHIPTS) Methods Seminar

Michael Shin, PhD
Associate Professor,
UCLA Department of Geography,
Geospatial @ UCLA

Tuesday, April 10, 2pm – 3pm

Center for Community Health, UCLA Wilshire Center
10920 Wilshire Blvd., Suite 350, Room 350-46 (Conference Room)

*** LIGHT REFRESHMENTS WILL BE SERVED ***
We will begin promptly at 2:00 p.m.

Health happens. What’s more is that health happens somewhere. Our understanding of how geography can define, shape, influence and inform health outcomes, policies, and interventions remains largely underdeveloped. This seminar provides an overview of how geospatial concepts, methods and approaches can complement and extend our understanding of health. Three brief analytical vignettes are presented to encourage and to stimulate further discussion on the potential of incorporating geospatial approaches into healthcare research, policies and interventions. First, variations in Medicare spending are situated and explored within a geographic framework. Second, the association between obesity and voting, and their respective and coincident geographies, are reviewed. Finally, results from a field experiment designed to increase civic engagement across Los Angeles are discussed in relation to making Angelenos healthier.

If you have any questions, please contact Dr. Sung-Jae Lee at sjlee@mednet.ucla.edu

This event is hosted by the Center for HIV Identification, Prevention, and Treatment Services (CHIPTS) and made possible by funds from the National Institute of Mental Health (MH058107).