Roll-out implementation optimization (ROIO) in Practice: Methodological Considerations and Case Examples

Dear Colleagues,

The UCLA CHIPTS Rapid, Rigorous, Relevant (3R) and the San Diego CFAR Implementation Science Hubs are co-hosting a methods workshop entitled, “Roll-out implementation optimization (ROIO) in Practice: Methodological Considerations and Case Examples,” on Friday, May 30, from 8:00 AM – 10:00 AM PT.  You don’t want to miss out on this workshop!

Featured Faculty: JD Smith, PhD, Anna Lau, PhD, Borsika Rabin, PhD, PharmD, MHP, Nicole Stadnick, PhD, MPH and Sylvanna M. Vargas, PhD, MPH

By the end of this workshop, participants will be able to:

  • Define the ROIO study design and explain how it differs from traditional stepped wedge and hybrid implementation-effectiveness designs.
  • Describe key methodological considerations for planning and executing a ROIO study, including timing of roll-out, adaptation tracking, and real-time optimization.
  • Identify appropriate contexts and research questions for which the ROIO design is best suited, with attention to health systems implementation.
  • Evaluate real-world case examples that illustrate application of ROIO methods across diverse clinical or public health settings.
  • Apply lessons learned from ROIO studies to conceptualize and refine their own implementation research designs, including opportunities for co-design, stakeholder engagement, and continuous learning.

There will be a 20-minute drop-in group consultation offered after the workshop for those who are interested.

REGISTER HERE or copy and paste link: https://tinyurl.com/5n87asnt

Feel free to share this opportunity with your network – all are welcome. A flyer is attached.

If you have any questions, contact ucla3rhub@mednet.ucla.edu.

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Methods for Rescuing Implementation Trials that Have Gone Off the Rails

Dear Colleagues,

We invite you to join the Center for Dissemination and Implementation at Stanford (C-DIAS), in collaboration with the UCLA CHIPTS 3R Implementation Science Hub, for an engaging panel discussion entitled “Methods for Rescuing Implementation Trials that Have Gone Off the Rails” on Tuesday, May 27, 2025, from 10 – 11:30 AM PT.

Featured panelists: Geoffrey Curran, PhD, Alison Hamilton, PhD, and JD Smith, PhD

Session description: In this panel, three principal investigators will describe how their extramurally funded implementation trials encountered potentially study-ending problems: Shifting context barriers (e.g., staffing, local policy, partner priorities) resulting in problems with site recruitment, retention, and/or engagement; missing data; mis-specified implementation strategies; and failed strategies.

To add this event to your Outlook calendar, click here calendar invite (or see attachment).

Join Zoom Meeting Here or use this link: https://northwestern.zoom.us/j/92083076417?pwd=cV6xWpfX5jmR2JM97k7nxdt0SU4KGQ.1

Feel free to share this announcement with your network.  Everyone is welcome.  No registration is required.

If you have any questions, contact Enrique Sanchez at eesanchez@mednet.ucla.edu 

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The power and pitfalls of social media strategies: Lessons learned from implementation science efforts to end the HIV epidemic

Dear Colleagues,

Please join our UCLA CHIPTS Implementation Science Hub for an upcoming Beachside Chat titled “The power and pitfalls of social media strategies: Lessons learned from implementation science efforts to end the HIV epidemic” on Friday, May 2, 2025, from 9 AM – 10 AM PT.

Featured panelists: Aimalohi Ahonkhai, MD, MPH, Jane Lee, PhD, LMSW, and Raquel Hernandez, MD, MPH

This chat will be moderated by Alison Hamilton, PhD, Tamra Loeb, PhD, and Elena Rosenberg-Carlson, MPH. This chat will be an interactive question and answer session on practical considerations and lessons learned from use of social media strategies in three HIV implementation science projects.

REGISTER HERE or copy and paste link: https://tinyurl.com/yvvvw7vc

Feel free to share this opportunity with your network – all are welcome. A flyer is attached.

If you have any questions, contact Enrique Sanchez at eesanchez@mednet.ucla.edu

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Global HIV and Implementation Science: Past, Present, and Future

The upcoming in-person Grand Rounds entitled, “Global HIV and Implementation Science: Past, Present, and Future,” will take place at BSRB 154 (UCLA) on Thursday, May 15, 2025, from 11:00 AM – 12:00 PM PT.

The event will feature Elvin H. Geng, MD, MPH:

  • Professor of Medicine, Division of Infectious Diseases, Washington University

Description: 

Dr. Geng will explore the evolution of implementation science in HIV care and treatment—celebrating past successes, confronting current challenges of funding instability, and embracing future opportunities to drive innovation and impact in a resource-constrained world

In-person Registration or Zoom Registration 

If you have any questions about the event or the Grand Round series, please contact Damilola Jolayemi at ojolayemi@mednet.ucla.edu.

A copy of the slides and recording will be posted after the event here: https://chipts.ucla.edu/training/hiv-grand-rounds/ 

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In Case You Missed It: Key highlights from CROI

Dear Colleagues,

CHIPTS is pleased to invite you to attend a virtual session entitled, “In Case You Missed It: Key highlights from the 2025 Conference on Retroviruses and Opportunistic Infections (CROI)” on Monday, April 21, 2025, from 2:00 PM – 3:00 PM PT.

Please note: This session was previously postponed and is now confirmed for Monday, April 21, 2025.

The purpose of this virtual session is to share key abstracts from CROI 2025 selected by CHIPTS scientists. Presenters will highlight innovative research specifically for CHIPTS community – including students, community members, healthcare providers, policymakers, researchers, and more – and discuss how new science can be applied to our collective efforts in eliminating the HIV epidemic.

REGISTER HERE or copy and paste link: https://tinyurl.com/mr24ds2v

If you have any questions, please contact Damilola Jolayemi (ojolayemi@mednet.ucla).

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An Innovative intervention for Sustainable HIV/AIDS Epidemic control in Zambia, in a quest to end the pandemic in Africa by 2030

The upcoming in-person Grand Rounds entitled, “An Innovative intervention for Sustainable HIV/AIDS Epidemic control in Zambia, in a quest to end the pandemic in Africa by 2030” will take place at CHS 13-105 (UCLA) on Tuesday, March 18, 2025, from 11:00 AM – 12:00 PM PT.

The event will feature Dr. Henry Fomundam:

  • Associate Professor, Howard University Department of Clinical and Administrative Pharmacy Sciences

Description: 

The presentation is on the Howard University’s differentiated service delivery (DSD- Plus) model which is an innovative approach that seeks to contribute to the national 2030 HIV epidemic control in Zambia. The DSD -Plus Model is a treatment quality assurance program that ensures adherence ,continuity in care (retention) and viral load suppression. Through such interventions, Zambia is among the six countries to have reached the UNAIDS95-95-95 targets for 2025.

In-person Registration or Zoom Registration 

If you have any questions about the event or the Grand Round series, please contact Damilola Jolayemi at ojolayemi@mednet.ucla.edu.

A copy of the slides and recording will be posted after the event here: https://chipts.ucla.edu/training/hiv-grand-rounds/ 

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Engaging community in implementation: State of the science and practice

Dear Colleagues,

We invite you to join our UCLA CHIPTS Implementation Science Hub for an upcoming Beachside Chat titled “Engaging community in implementation: State of the science and practice” on Friday, February 21, 2025, from 11 AM – 12PM PT.  More information provided below.

Featured speakers: Rajinder (Sonia) Singh, PhD, and Eva Woodward, PhD.

This Beachside Chat series is led by the UCLA CHIPTS Implementation Science Hub, supported by Ending the HIV Epidemic supplement awards from the National Institutes of Health.

This chat is hosted by Dr. Alison Hamilton, featuring panelists Drs. Rajinder (Sonia) Singh and Eva Woodward on engaging community in implementation. This chat will be interactive question and answer session on the state of the science on engaging community members in implementation science and practice efforts.

REGISTER HERE or copy and paste link: https://tinyurl.com/ys8zsy7w

Feel free to share this opportunity with your network – all are welcome. A flyer is attached.

If you have any questions, contact eesanchez@mednet.ucla.edu

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HIV-specific antibody responses after early ART initiation: obstacles and opportunities

The upcoming in-person Grand Rounds entitled, “HIV-specific antibody responses after early ART initiation: obstacles and opportunities” will take place at CHS 13-105 (UCLA) on Tuesday, January 14, 2025, from 11:00 AM – 12:00 PM PT.

The event will feature Katharine J Bar, MD:

  • Director, Penn CFAR Virus and Reservoirs Core, Perelman School of Medicine, University of Pennsylvania

Description: 

HIV-1 has evolved to be uniquely resistant to antibody neutralization, such that antibody responses fail to clear or control the virus. Early initiation of antiretroviral therapy (ART) limits HIV reservoir size and diversity and preserves immunity. We characterized the impact of acute and early ART initiation on the development of HIV-specific antibody responses. We found that acute ART initiation (prior to 60 days) prevented autologous neutralizing antibodies from developing before or on ART. Early ART initiation (60-120 days) allowed neutralizing antibody development prior to ART, which continued to expand in breadth and potency over years of suppressive ART. We found similar antibody kinetics in a nonhuman primate (NHP) model of early ART initiation. Together, results provide optimism that we could use new vaccine techniques to boost autologous antibodies to cover the unique diversity of viruses within early treated NHP and humans.

In-person Registration or Zoom Registration 

If you have any questions about the event or the Grand Round series, please contact Damilola Jolayemi at ojolayemi@mednet.ucla.edu.

A copy of the slides and recording will be posted after the event here: https://chipts.ucla.edu/training/hiv-grand-rounds/ 

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Addiction Medicine is Medicine: Integrating Care to End the HIV Epidemic

The upcoming in-person Grand Rounds entitled, “Addiction Medicine is Medicine: Integrating Care to End the HIV Epidemic” will take place at BSRB 154 (UCLA) on Tuesday, November 12, 2024, from 11:00 AM – 12:00 PM, PT.

The event will feature Ellen F Eaton MD, MSPH, FIDSA:

  • Associate Professor of Medicine, University of Alabama at Birmingham

Description: 

Dr. Eaton will highlight addiction medicine as integral to comprehensive medical care. Attendees will be able to understand stigma as a barrier to health equity and strategies to create an inclusive HIV treatment environment.
Attendees will be able to identify opportunities to integrate substance use and Infection prevention and treatment in both acute and community settings.

Register here or Copy and paste link: https://uclahs.zoom.us/j/95745228613

If you have any questions about the event or the Grand Round series, please contact Damilola Jolayemi at ojolayemi@mednet.ucla.edu.

A copy of the slides and recording will be posted after the event.

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Expanding PrEP use in Los Angeles County: 2024 and Beyond

Dear colleagues,

We are delighted to invite you to the FINAL workshop hosted by our Equitable Injectable PrEP in LA County Initiative. Here are details for the upcoming workshop:

  • Title: Expanding PrEP use in Los Angeles County: 2024 and Beyond
  • Date: Tuesday, October 29, 2024
  • Time & Place: 10:00 AM – 11:30 AM PT via Zoom
  • Description: The workshop will feature a panel presentation from staff at the Division of HIV and STD Programs on current and future plans to expand PrEP use in Los Angeles County.
  • Registration Link: https://uclahs.zoom.us/webinar/register/WN_a6vqIyThRb6RvehS34bSow#/registration

The primary audience for this workshop is HIV service providers and their staff. All are welcome.

Please share this opportunity with your networks. A flyer is attached.

If you have any questions, please contact Elena Rosenberg-Carlson at erosenberg-carlson@mednet.ucla.edu.

www.chipts.ucla.edu

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