Clinical trial will compare three antiretroviral drug regimens.

The National Institutes of Health has launched a large international study to compare the safety and efficacy of three antiretroviral treatment regimens for pregnant women living with HIV and the safety of these regimens for their infants. The study will evaluate the current preferred first-line regimen for pregnant women recommended by the World Health Organization (WHO) and two regimens containing newer antiretroviral drugs that are becoming more widely used. It will provide data on the use of these newer drugs during pregnancy, helping to ensure that women living with HIV and their infants receive the best available treatments.

Each year worldwide, an estimated 1.5 million women living with HIV give birth. Previous research has clearly demonstrated that antiretroviral therapy to suppress HIV prevents perinatal HIV transmission and benefits the health of both mother and child. In the new study, investigators will compare the virologic efficacy of the three regimens….

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