Elevated genital concentrations of HIV target cell-recruiting chemokines and a genital inflammatory profile contributes to the high risk of HIV acquisition in these African women…….In conclusion, susceptibility to HIV infection was associated with elevations in genital inflammatory cytokines, as a marker of genital inflammation. The increased frequency of 4 inflammatory cytokines in younger women may be an important driver of the high HIV incidence rates in young women in Africa.

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