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Feature/News

IAS 2017 – Dr. Landovitz presents on the results of HPTN-077

July 25, 2017, Paris, France – Dr. Landovitz, CHIPTS Co-Director, spoke on the “Enhancing the Impact of HIV Prevention” press conference regarding the findings of HPTN-077 at the 9th International AIDS Society Conference on HIV Science in Paris, France.

 

Photo ©IAS/Steve Forrest/Workers' Photos

Photo ©IAS/Steve Forrest/Workers’ Photos

A previous phase 2a study of US males that used a dose of 800mL of cabotegrovir administered every 3 months did not consistently meet the pharmacokinetics  standards. Due to this study, HPTN-077 studied not only a dosage of 800 mL in males and females administered every 3 months, but also a model dose of 600 mL every 8 weeks. HPTN-077 is a phase 2a study designed to measure the safety tolerability, acceptability, and pharmacokinetics of Cabotegravir.

Dr. Landovitz goes on to describe how HPTN-077 was conducted and its positive results, saying that they were “very supportive for moving forward into phase 3 efficacy studies with the 600 mL dose” noting that such a study was already in the field with HPTN-083 while HPTN-084 is currently in development.

The press conference included presentations from Jean-Michel Molina, Ayesha Kharsany, Andrew Grulich, Catherine Oldenburg, and moderator Linda-Gail Bekker and concluded with questions from the audience.

To see the entirety of Dr. Landovitz presentation, click on the photo below! Dr. Landovitz’s presentation begins at the the 7:05 mark.

Photo ©IAS/Steve Forrest/Workers' Photos

Photo ©IAS/Steve Forrest/Workers’ Photos

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