Uganda HIV Voluntary Counseling and Testing Study

At a glance:

Project Name

Uganda HIV Voluntary Counseling and Testing Study

Brief Overview

The Uganda HIV Voluntary Counseling and Testing (VCT) Study is a randomized clinical trial to evaluate strategies for optimizing risk reduction within the context of routine HIV VCT (rVCT) and fully integrating inpatient counseling and testing with post-discharge HIV medical care to ensure that diagnosed individuals receive access to care.

Geographical Location: Kampala, Uganda

Target Population: Patients from inpatient wards and outpatient clinics of Mulago Hospital inKampala,Uganda

Intervention Model: Social Action Model

Research Methods:

The first intervention compares, in a non-inferiority study design, in-patient/outpatient routine counseling and testing (rVCT) with traditional HIV pre- and post-test counseling and testing (tVCT). The second intervention compares, in a superiority design, an “enhanced linkage to care” model for seropositive persons to increase uptake and long-term utilization of HIV-specific medical care compared to routine discharge and referral.

 Local significance (How has this project impacted the immediate population?):

This project provides HIV testing and linkages to care for patients from inpatient wards and outpatient clinics at the study site.

International significance (How has this project impacted the global community?):

This study will describe VCT and linkage to care among hospitalized patients in a resource-limited setting. As ART becomes more accessible throughout the developing world, the utility of inpatient VCT and linkage to care will likely lead to widespread adoption. This study will be a step toward creating a program and materials to enable rapid and low-cost dissemination to other settings in resource-limited countries. We will model the impact of behavioral risk reduction and estimated reductions in infectiousness due to estimated antiretroviral-mediated viral suppression, to determine the optimal strategy from an HIV prevention perspective.