HIV R4P Satellite Session on Long-Acting Injectables for HIV Prevention and Treatment

We held our pre-conference satellite session, “It Only Hurts a Little: Long-Acting Injectables for HIV Prevention and Treatment,” at the HIV Research For Prevention (HIVR4P) Conference in Madrid, Spain on Monday, October 22, 2018. With a full house, we had great conversations on both of our moderated panels discussing the clinical, behavioral, policy, and community considerations associated with the implementation of long-acting injectable antiretrovirals for both HIV prevention and treatment.

We, at the Center for HIV Identification, Prevention, and Treatment Services (CHIPTS), were thrilled to hold this satellite session in collaboration with the HIV Prevention Trials Network, AIDS Clinical Trials Group, and UCLA Center for AIDS Research.

Photos from the event will be up soon so make sure to like our Facebook page or follow us on Twitter for the latest updates! To learn more about future events such as this one, make sure to subscribe to our listserv.

Agenda

11:30   Lunch and Registration

12:00   Welcome

12:10   Opening Remarks – Steve Shoptaw, PhD

12:20   Panel 1: Preparing for Long Acting Injectable for Prevention

  • Raphael Landovitz, MD, MSc (Moderator)
    CHIPTS, University of California, Los Angeles, USA
  • Beatriz Grinsztejn, MD, PhD
    Instituto Nacional de Infectologia Evandro Chagas-Fiocruz, Brazil
  • Nyaradzo M. Mgodi, MBChB, MMed
    University of Zimbabwe –University of California, San Francisco, USA
  • Giang Minh Le, MD, PhD
    Hanoi Medical University, Vietnam
  • Elizabeth Gardiner
    AVAC, USA

1:30     Break

1:40     Panel 2: Preparing for Long Acting Injectable for Treatment

  • Aadia Rana, MD (Moderator)
    University of Alabama-Birmingham, USA
  • Linda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD
    Desmond Tutu HIV Centre, University of Cape Town, South Africa
  • Santiago Moreno, PhD
    University of Alcala de Henares, Spain
  • Omar Sued, MD, MSc, PhD
    Fundación Huésped, Buenos Aires, Argentina
  • Jonathan Lucas, MPH
    HIV Prevention Trials Network (HPTN)

2:50     Closing Remarks

3:00     Adjourn

Download the PDF flyer here: Long-Acting Injectables for HIV Prev and Treatment - Flyer
Download the PDF agenda here:  Long-Acting Injectables for HIV Prev and Treatment - Agenda
Download the PDF panelist bios here:  Long-Acting Injectables for HIV Prevention and Treatment - Panelist Biographies

HHS Awards $2.34 Billion in Grants to Help Americans Access HIV/AIDS Care and Medication

This article originally appeared on hiv.gov. To see the full article click here

Today, the U.S. Department of Health and Human Services announced that approximately $2.34 billion in Ryan White HIV/AIDS Program grants were awarded to cities, counties, states, and local community-based organizations in fiscal year (FY) 2018. This funding through the Health Resources and Services Administration (HRSA) supports a comprehensive system of HIV primary medical care, medication, and essential support services to more than half a million people living with HIV in the United States.

“New medical advances and broader access to treatment have helped transform HIV/AIDS from a likely death sentence into a manageable chronic disease,” said HHS Secretary Alex Azar. “The Ryan White HIV/AIDS Program is an important way to ensure that these life-saving treatments reach the Americans who need them, and the Trump Administration is committed to continuing to improve the care by Americans living with HIV/AIDS receive.”

“The Ryan White HIV/AIDS Program plays a vital role in the United States’ public health response to ending the HIV epidemic,” said HRSA Administrator George Sigounas, M.S., Ph.D. “These grants will help ensure that the most vulnerable Americans living with HIV/AIDS have access to life-saving care and treatment needed to improve their health quality and medical outcomes.”

HRSA oversees the Ryan White HIV/AIDS Program, which is a patient-centered system that provides care and treatment services to low income people living with HIV to improve health outcomes and reduce HIV transmission among hard to reach populations. The program serves approximately 50 percent of people living with diagnosed HIV infection in the United States. In 2016, approximately 85 percent of Ryan White HIV/AIDS Program clients who received HIV medical care were virally suppressed, up from 69 percent in 2010.

“The Ryan White HIV/AIDS Program is critical to improving clinical and public health outcomes by reducing HIV transmission and serves as an important source of ongoing access to HIV treatment and antiretroviral medication,” said Laura Cheever, M.D., Sc.M., Associate Administrator, HIV/AIDS Bureau. “Today people living with HIV who take HIV medication daily as prescribed and who achieve and maintain an undetectable viral load have effectively no risk of sexually transmitting the virus to an HIV-negative partner.”

Under Part A of the Ryan White HIV/AIDS Program, approximately $624.3 million was awarded to 52 metropolitan areas to provide core medical and support services for people living with HIV. These grants were awarded to 24 eligible metropolitan areas and 28 transitional grant areas with the highest number of people living with HIV and AIDS and experiencing increases in HIV and AIDS cases and emerging care needs. For a list of the FY 2018 Ryan White HIV/AIDS Program Part A award recipients, visit https://hab.hrsa.gov/awards/fy-2018-ryan-white-hivaids-program-part-a-final-awards….

(Full Article)

HUD Awards $23 Million to Renew Support to 22 Local HIV-AIDS Housing Programs

WASHINGTON – The U.S. Department of Housing and Urban Development (HUD) on August 29 announced $23 million to assist more than 1,700 low-income persons living with HIV/AIDS and their families annually over a three-year period. The funding announced today is offered through HUD’s Housing Opportunities for Persons with AIDS Program (HOPWA)  and will renew HUD’s support of 22 local programs. These grants provide a combination of housing assistance and supportive services for this vulnerable population.

“We recognize the profound effect stable housing can have on a person trying to manage their health,” said HUD Secretary Ben Carson. “Working closely with our partners on the ground, these grants will provide critically needed housing and care for low-income persons living with HIV/AIDS.”

Research shows that a stable home is critical to the well-being of persons living with HIV/AIDS, and results in better health outcomes and reduced transmission of the disease. In addition to housing assistance, these local programs will provide access to supportive services such as case management, mental health services, substance abuse services, and employment training. The combination of housing assistance and supportive services are critical in sustaining housing stability, promoting better health outcomes, and increasing quality of life, which promotes self-sufficiency efforts for those able to transition to the private housing market…

(Full Article)

Spotlight: Corrina Moucheraud, ScD, MPH

Corrina Moucheraud, MPH, ScD is an Assistant Professor in the Fielding School of Public Health, in the Department of Health Policy and Management and her research focuses on global health policy and systems. She uses quantitative and qualitative data to answer questions about how to effectively and equitably deliver high-quality health care in low-resource settings.

Corrina grew up in New York City and was obsessed with disease epidemics from a young age. She had planned to become a doctor with Doctors Without Borders and  had even spent time after school during her teenage years as a volunteer in their office.  Eventually, Corrina realized that her true love was health – so after a short-lived stint of undergrad pre-med, she began happily studying and working in global public health. She received her Master of Public Health degree from the University of North Carolina at Chapel Hill, in Health Behavior as well as her Doctor of Science degree from the Harvard T.H. Chan School of Public Health, in Global Health and Population.

Currently, Corrina participates in an ongoing collaboration between faculty at the UCLA Geffen School of Medicine and partners in Malawi, focused on care for HIV and other chronic diseases such as cervical cancer and hypertension in the HIV-positive population. Her research on cervical cancer in Malawi is the focus of a recent career development award (KL2) from the Clinical and Translational Science Institute (CTSI).

Corrina also serves as Co-Principal Investigator of a project that involves CHIPTS faculty Arleen Leibowitz, Ian Holloway and Nina Harawa, alongside investigators from the University of Southern California, and in partnership with the Los Angeles County Department of HIV and STI Programs (DHSP).  The project aims to examine approaches for “getting to zero” among men who have sex with men in Los Angeles County. This is an exciting opportunity that applies research methods to inform real-world planning and priority-setting and has the potential to have meaningful impact on service planning in Los Angeles.  This research is supported by a seed grant from the UCLA AIDS Institute, UCLA Center for AIDS Research (AI28697) and USC Molecular Microbiology and Immunology.

As a native of another large and diverse city, Corrina loves living in Los Angeles. She and her partner moved here in 2015, and have been avid weekend explorers ever since. They particularly enjoy sights and experiences that are off the beaten track, so they are always looking for suggestions of eccentric, unusual or underappreciated gems in the LA area!

Each month, we’re featuring a member of our CHIPTS family and their work! To see past spotlights, check them out on the spotlights page and make sure to check back to see who we feature next!

Colloquium: “NUMBERS and VOICES: A Profile of PrEP among Latino MSM in Los Angeles County”

Amanda Landrian Gonzalez

September 13, 2018 – Dr. Ron Brooks, Omar Nieto, and Amanda Landrian Gonzalez

presented “NUMBERS and VOICES: A Profile of PrEP among Latino MSM in Los Angeles County” at this month’s HIV Research and Community Colloquia series at the Los Angeles County Commission on HIV meeting. The presentation used both quantitative and qualitative data to provide a profile of PrEP-related issues among Latino men who have sex with men (MSM) in Los Angeles County. The presentation looked at both Latino MSM non PrEP users and PrEP users.

Omar Nieto

For non-PrEP users, they expounded on the demographic and behavioral predictors of awareness, accessibility, and acceptability of PrEP among Latino MSM. For PrEP users, and explored the lived experiences of Latino MSM who are using PrEP, including motivations for initiating PrEP, challenges in accessing PrEP, and experiences with PrEP stigma. Based on the findings from the two studies, they provided recommendations of how service providers, health departments, and other community stakeholders may help optimize uptake of and persistent use of PrEP among Latino MSM.

The full presentation is available on Youtube and below and the you can download the presentation slides as well.

Numbers and Voices: A Profile of PrEP among Latino MSM in Los Angeles County - Slides

CHIPTS hosts a monthly HIV Research and Community Colloquia Series in collaboration with the Los Angeles County Commission on HIV to highlight current issues and conversations surrounding HIV. Click here for past lectures and check out the events page for more information on future Colloquia presentations!

New Tools and Information from the CDC about HIV Treatment, Care and Prevention

Access CDC’s Latest Tools and Information for HIV Care Providers about HIV Treatment and Care

The Centers for Disease Control and Prevention (CDC) launched new tools and information for HIV care providers on its Prevention IS Care website, highlighting the latest science and guidance from CDC on HIV treatment and care and transmission prevention. This new content can help you start the conversation with your patients about HIV treatment, care, and transmission prevention strategies. LEARN MORE

HIV care providers can access:

  • A new HIV treatment and care webpage, featuring information to help you implement HIV prevention and care recommendations, including sample questions to get the conversation started with patients, evidence-based approaches for retention in care, and how to build trust with patients.
  • A new transmission prevention webpage, highlighting the benefits of treatment as prevention, prevention methods, and what is known about each method for different modes of transmission.

Talk to your patients about HIV treatment, care, and transmission prevention to help them live longer, healthier lives. Because a patient’s needs may change over time, HIV care providers should engage patients in brief conversations at every visit to discuss the prevention steps the patient is taking.

NIH launches study to test combination antibody treatment for HIV infection

“Antiretroviral therapy suppresses HIV to very low levels, normalizes life expectancy, and prevents sexual transmission of the virus. However, these benefits are lost if an individual stops taking the medications as prescribed,” said Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), part of NIH. “If proven safe and effective, periodic infusions of potent, broadly neutralizing HIV antibodies may be a potential alternative to daily antiretroviral therapy.”

(Full Article)

Novel intervention halves rate of death among people living with HIV who inject drugs

This article originally appeared on NIH.gov. To access the original article, click here

An intervention designed to facilitate treatment for HIV and substance use was associated with a 50 percent reduction in mortality for people living with HIV who inject illicit drugs, a study has found. In addition, the people who received the intervention were nearly twice as likely to report being in treatment for HIV and substance use after one year as those who received their national standard of care. They also were about twice as likely to have suppressed their HIV to undetectable levels after one year. The intervention consisted of psychosocial counseling along with guidance and support navigating the healthcare system. These findings were reported today in the journal The Lancet.

People who inject drugs often have high rates of HIV infection, poor access to and use of treatment for HIV and substance use, and high mortality in the United States and globally. Needle sharing among people who inject drugs is the main route of HIV transmission in some parts of the world.

“People living with HIV who inject drugs often encounter multiple obstacles to beginning and adhering to treatment for HIV infection and substance use,” said Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. “This study demonstrates that providing guidance and counseling can help such individuals overcome barriers to starting and staying in care and treatment, leading to a significantly higher rate of HIV suppression and a much lower rate of death.”

(Full Article)

Opioid and HIV in Los Angeles: Getting the Word Out to Communities and Providers

The event on “Opioid and HIV in Los Angeles: Getting the Word Out to Communities and Providers” took place at St. Anne’s on September 24, 2018 from 9 AM – 12:30 PM. The purpose of this event is to increase awareness and to provide information for service providers, community members and clients about the current opioid crisis and its associated link to HIV. Speakers include Steve Shoptaw, Gary Tsai, Shoshanna Scholar, Michael Marquesen, Jose Salazar, Ayako Miyashita Ochoa, Ward Carpenter, Wendy Garland and more.

The event is to provide training and to increase awareness among clinical providers (RNs, MDs), HIV service providers, mental health specialists (MFTs, LCSW), substance abuse counselors, case managers, and community advocates about the national and local opioid epidemic and its impact on HIV infections. The training will provide attendees with the necessary information and skills needed to engage and to discuss with their clients about the risks of opioid misuse, dangers of fentanyl, and various harm reduction/overdose prevention strategies.

Objectives of this meeting are to: increase participants’ awareness of the national opioid epidemic, its associated HIV risks, and upcoming opioid-related research initiatives; increase participants’ knowledge of the opioid crisis in Los Angeles County and the various county-wide initiatives that are being implemented to address the opioid problem; increase participants’ knowledge regarding medication for addiction treatment programs, fentanyl screening, overdose prevention strategies, and other referral resources.

You can find our event gallery on our Facebook page!

Download the agenda, flyer, and the speakers’ biographies below:

Opioid and HIV in Los Angeles: Getting the Word Out to Communities and Providers - Flyer
Opioid and HIV in Los Angeles: Getting the Word Out to Communities and Providers - Agenda
Opioid and HIV in Los Angeles: Getting the Word Out to Communities and Providers Speakers - Biographies

Slides for each presentation are available for download below:

National Overview of the Opioid Crisis: Intersection with HIV - Slides
The Opioid Crisis in Los Angeles County - Slides
Medication for Addiction Treatment (MAT) Expansion Project - Slides
Overdose Prevention Programs in LAC Jails - Slides
AB 196: Safer Drug Consumption Sites - Slides
Substance Use Among Persons at Risk for and Living with HIV in LA County - Slides

NIH officials: closing treatment gaps critical to ending the U.S. HIV epidemic

The following is an excerpt from NIH.gov. To read the full article, click here

Daily antiretroviral therapy (ART) that suppresses HIV to levels undetectable by standard blood tests is lifesaving for individuals living with HIV and prevents sexual transmission of the virus to others. The public health community must use targeted interventions, however, to do a better job of reaching populations with low levels of viral suppression, according to experts from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

If HIV treatment as prevention is to help us reach the goal of ending the HIV epidemic in the United States, it is critical to understand, address and bridge gaps in achieving viral suppression, NIAID Director Anthony S. Fauci, M.D., and colleagues write in an editorial commenting on an NIH-funded study published in Annals of Internal Medicine. (Full Article)